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17/Dec/2023

STEM CELL (FIBROBLAST)

Treating disease and preventing aging have been the driving forces of medicine since the early days of humanity. New treatment methods have emerged for these purposes with the recent advances in medicine and biotechnology. The most remarkable of these methods is “Stem Cell”. The journal, Science, has shown advances in “Stem Cells” among the 10 most significant medical developments. Stem cells have now become a preferred treatment option in dermatology in recent years due to their properties aiding repair and new collagen production. They are used in the treatment of skin defects in particular, and to treat facial loss of volume, acne, surgical scars, body contour disorders and widespread epidermis losses as seen in burns and with epidermolysis, and also to aid breast enlargement and skin rejuvenation due to their self-renewal and differentiation properties.Stem cells are the main source of all cells in our body and have the capacity to divide and renew themselves. They can therefore help damaged tissue to reproduce and regain its former function. However, stem cell treatments require a multidisciplinary approach including the indication-specific clinical sciences as well as cell biology, embryology, tissue engineering, molecular biology and genetic sciences.The currently preferred stem cell sources for skin rejuvenation are mesenchymal stem cells obtained from the skin and fat tissue. Fat tissue has a relatively abundant number of stem cells but the need for surgery and the high and rapid rate of melting has decreased the demand for fat tissue. New sources of stem cell have therefore been investigated and the interest in the skin has gradually increased.

The stem cell model is primarily used for skin rejuvenation and the correction of skin defects is based on fibroblasts obtained from the skin.

Fibroblasts are the main functional cells of the skin. They are responsible for the synthesis of collagen and glycosaminoglycan providing the structural integrity of the skin. Besides, they play a major role in wound healing. Stem cell treatment has therefore been used for skin rejuvenation and the correction of skin defects since 1995.

How are STEM CELLS obtained?

The preferred area for obtaining stem cells is the area behind the ear. This region is protected from the sun and there is therefore minimal DNA damage. A small biopsy of 0.3- 0.6 cm is taken from the region. Approximately 50 cc of blood is also drawn to be used for the reproduction of fibroblasts. The tissue and blood samples obtained under sterile conditions are sent under appropriate conditions to a stem cell laboratory approved by the Ministry of Health. When the desired density is reached following approximately 3 to 6 weeks of stem cell reproduction, the fibroblasts are drawn into a syringe under sterile conditions and delivered to the physician who then administers them to the desired area with 1 cm intervals. Stem cell administration is performed in 3 sessions with intervals of 3-6 weeks.

Which regions are STEM CELLS applied to?

Fibroblast stem cells obtained from the skin can be applied to any area where rejuvenation is desired. However, the most common areas of application are the face, neck, décolletage area and hands. These cells are also used for sagging around the eyes, treatment of spots, correction of scar tissue on the face and body, and the treatment of skin diseases that cause loss of skin. The stem cells obtained from a hair biopsy are also used successfully in many disorders that cause hair loss, and especially male and female type hair loss (androgenetic alopecia).

How long is STEM CELL treatment effective for?

Although the effect is noticed immediately after the first session, the maximum effect is observed between the 6th and 12th months. The skin becomes younger 5-10 years after stem cell applications for skin rejuvenation. For example, a 45-year-old person will have the skin quality of someone 35 to 40 years old after 3 sessions of stem cell therapy and will maintain this effect for 5 to 10 years on average depending on genetic, structural and environmental factors. Stem cells will continue to produce new fibroblasts over the years and the effect duration is much longer than with other cosmetic procedures.

Are STEM CELL applications safe?

Stem cell treatment has been accepted as a safe method in various studies conducted since its first use. The application of fibroblast stem cells obtained from the skin was the first stem cell treatment approved for skin rejuvenation by the US Food and Drug Administration (FDA) and was approved in 2011. It does not cause any allergies or toxic effects because it is obtained from the individual’s own cells. It enables recovery of the fibroblasts lost in time and stimulates the skin in the most natural way.

What are the important issues after STEM CELL application?

It is possible for patients to continue their work and social life after stem cell use.


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01/Dec/2023

We will introduce this branch of surgery by dividing it into two as “Plastic and Reconstructive” Surgery and “Aesthetic” Surgery.

Plastic and Reconstructive Surgery (Reconstruction and Repair Surgery)
Plastic and Reconstructive Surgery; It is a branch of surgery that tries to eliminate congenital or acquired anomalies, deformities and dysfunctions and to correct body image. Plastic is a word that comes from the Greek “plasticos” and means “to shape”, “to fit into a mold”. Reconstructive, on the other hand, is a word of Latin origin and means “to remake”.

Plastic and Reconstructive Surgery deals with all kinds of surgical problems that occur on the entire body surface. Events that disrupt the shape and functions of the body may be congenital, traumatic or acquired. For example; congenital cleft palate-lip, conjoined finger (syndactyly), vascular masses (such as hemangiomas); traumatic burns, facial injuries due to traffic accidents, various incisions and organ ruptures; various acquired skin and soft tissue tumors, chronic wounds are within the scope of this surgical discipline. Losses, deformities, pathological events (tumors, cysts, infections, etc.) in bone (especially facial, head and hand bones) and cartilage (such as ear and nasal cartilages) are also within the field of plastic surgery. In addition to classical surgical methods, microsurgery, laser systems, endoscopy and various chemical agents and drugs can be used for this purpose.

 

In summary; Plastic and Reconstructive Surgery tries to repair all kinds of defects (cavities) affecting the skin, subcutaneous tissue and bones on the entire body surface. The basic rule in doing this is to repair with tissues similar to the tissues that have been lost.

Areas of interest in Plastic and Reconstructive Surgery:

– Facial deformities – Asymmetries, congenital masses, rare facial clefts
– Cleft lip and palate
– Craniofacial – maxillofacial anomalies (e.g. deformities, irregularities, deficiencies of the jaw, face and skull bones
– Orthognathic surgery (Jaw closure disorders)
– Absence of auricle, prominent ear and other deformities
– Nasal defects, tumors, ruptures
– Salivary gland problems
– Congenital tumors, nevi (moles), masses, vascular malformations, hemangiomas
– Bone and soft tissue trauma of the face
– Maxillofacial surgery (Bone defects-fractures-shape and function disorders caused by traffic accidents, tumors and other causes, jaw surgery
– Head and neck tumors and repair of their defects
– Absence, asymmetry or excess breast tissue
– Breast reconstruction after cancer
– Gynecomastia (large breast in men)
– Congenital anomalies of the genital organs (Epispadias, hypospadias, vaginal agenesis etc.)
– Repairs of genital organs, replantation of severed organs,
– Chest and abdominal wall defects
– Hand Surgery (Traumas, tumors, finger transfers, finger repairs-extensions etc.)
– Deficiencies and deformities of the hands and feet
– Peripheral nerve problems (traumas, neuropathies, defects, masses)
– Skin and soft tissue tumors
– Acute burns and post-burn deformities, contractions, shrinkage, damage to soft tissues caused by electrical and chemical substances
– Skin and subcutaneous wounds caused by various infections, radiation and other influences
– Chronic wounds (such as pressure sores, venous wounds, diabetic foot wounds)

The rule for repair in Plastic Surgery is to choose the simplest and least damaging method first. Primary repair of a wound (such as suturing) is considered first, and if there is tissue loss, graft (skin patch) application comes to the agenda. In cases where this method is not suitable (such as deep and complex tissue loss, open bone and tendon injuries), flaps should be used. Flaps are planned in a flow chart from local simple flaps (for example skin flaps) to composite flaps (involving more than one tissue) depending on the condition and location of the tissue defect. The basic rule in plastic surgery is to repair by using the tissues closest to the lost tissues. In both plastic surgery and aesthetic surgery, it is primarily appropriate to use autologous tissues (taken from the person himself/herself). However, if donor areas or the patient is not suitable for autologous tissues, other sources can be used (homografts, heterografts and alloplastic materials). For example, for extensive burns, skin grafts (skin patches) from intact areas of the patient are preferred. If these areas are insufficient, skin from other people, cadavers (homografts) and even skin from animals (heterografts) can be used. With the exception of autografts, they are used as temporary biological dressings in humans and are not retained in the wound. Another example can be given for bone loss. In facial bone loss, bone is first taken from other body parts and applied to the defect area. However, if this source is insufficient or unavailable, alloplastic materials (porous polyethylene, hydroxyapatite, titanium, etc.) can be used.

Aesthetic Surgery (Cosmetic Surgery)

It is a sub-branch within plastic surgery. Aesthetic (or cosmetic) surgery deals with operations and interventions to make the body image more beautiful and perfect. There are aesthetic problems here rather than a medical problem. In the media, there is more news about the aesthetic aspect of plastic surgery, and perhaps for this reason, the public perceives plastic surgeons as people who only perform plastic surgery. However, plastic surgeons mostly deal with repair surgery (reconstructive surgery) in clinics.
All plastic surgeons also receive plastic surgery training during their specialty training and they are the only surgeons authorized to perform these operations. Aesthetic surgery requires long training and experience. Such operations require both surgical and artistic talent. In plastic surgery, not always aesthetic, but sometimes medical problems are solved. For example, surgical correction of an overweight body or breasts that have grown to giant sizes (gigantomastia) solves both medical and aesthetic problems. In addition to the aesthetic correction of an organ, its function is also extremely important. For example: in aesthetic nose surgery (Rhinoplasty), shape and breathing problems must be corrected together.

In our country, breast plastic surgery (enlargement-reduction-lift), nose plastic surgery (rhinoplasty), body contour surgery (liposuction, lipectomy, abdominoplasty), face lift-renewal, eyelid surgery (blepharoplasty), auricle correction (protruding ear) are frequently performed. It is among the aesthetic operations performed.

For aesthetic surgery operations, it is necessary to consult expert plastic surgeons. The attempts of doctors in other fields to perform plastic surgery create many medical, ethical and judicial problems, and patients in incompetent hands encounter complications that are very difficult to correct. Therefore, it would be to the benefit of patients to consult “Plastic and Aesthetic Surgeons” when choosing a surgeon regarding the above problems.

Fields of Aesthetic Surgery

·    Aesthetic and functional nose correction (Rhinoplasty, septorhinoplasty)
·    Facial renewal (Face lift – eyelid and mouth area revisions, treatment of wrinkles)
·    Endoscopic face-forehead lift, eyebrow lift
·    Eyelid aesthetics (Blepharoplasty)
·    Correction of prominent ears and other aesthetic problems in the auricle,
·    Jaw enlargement and reduction operations (Mentoplasty),
·    Removing scars and irregularities on the skin,
·    Hair transplants-replacements
·    Laser applications (Face peeling, removal of blemishes and vascular malformations
·    Aesthetic breast operations: Enlargement, reduction and lift
·    Operations to reduce excessive skin-subcutaneous fat tissue (liposuction-lipectomy)
·    Tummy tuck (Abdominoplasty)
·    Leg contour correction (with liposuction, injections or leg implants)
·    Contour corrections with implants (prostheses applied to soft tissue) (such as hip and thigh implants, pectoral (chest) implants in men – leg implants)
·    Skin care and interventions

To achieve the goal in aesthetic surgery, operative and non-operative methods can be used together or separately. For example, in facial rejuvenation, first a face lift (rhytidectomy = face lift) is performed, then chemical peeling and filler injection can be performed for fine lines and blemishes. It should not be forgotten that aesthetic problems that require surgery (such as sagging skin, regional fat accumulation, hypertrophic breast) can only be resolved with operative methods. Instead of surgery, some methods (mesotherapy, carboxytherapy, etc.), whose scientific validity has not yet been proven and are generally applied by people other than plastic surgeons, do not provide any significant benefit to patients.

Apart from the major operations listed above in aesthetic surgery, skin peeling methods (laser, chemical or mechanical peeling) for blemishes, fine wrinkles, acne or old scars; fat injections (lipofilling) for dimples and contour disorders; fillers (such as collagen, hyaluronic acid) for depressed scars and wrinkles; Auxiliary methods such as applications for forehead and eye lines, injection of fat and various fillers for lip thickening are applied.

Turkish Plastic Surgery has a very good place in the world both in terms of scientific and surgical talent. All plastic and aesthetic surgery operations performed in the world can be performed with the same quality in our country, and many foreign patients come to our country and undergo surgery.

Specialized sub-branches within Plastic Surgery:
Aesthetic (Cosmetic) Surgery: These are operations performed to give the patient a more aesthetic and proportionate body. The relevant body part (nose, breast, abdomen) is made more perfect and compatible with the surrounding contours based on anatomical and aesthetic measurements. Fat injections and various implants can be used in this surgery.

Maxillofacial Surgery: Deals with all types of surgery of the facial bones. Correction of facial bone fractures, tumors, orthognathic corrections (moving the jaws forward or backward), and congenital facial clefts are within this field.

Craniofacial Surgery: Corrects abnormalities and deformities in the skull bones. Skull deformities (tower head, hammer head, flattened head) noticed after birth are corrected through craniofacial surgery, as they will negatively affect brain development. Defects and deformities that occur later in the skull bones can be repaired with various autologous tissue (bone and cartilage taken from elsewhere) or alloplastic materials.

Microsurgery: It is a surgery performed under an operating microscope with special microsurgical instruments. Replantation of severed hands, feet and other tissues can be done with this surgical technique. Thanks to the suturing of small diameter vessels and nerves, the function of the severed organ is restored, and it is also possible to transfer tissues from another region to a defect (Free flaps). Today, thin vessels and nerves up to 0.5 mm in diameter can be sutured.

Hand Surgery: Correction of traumatic (cuts, crushes, ruptures) defects, shape and function disorders in the hand, correction of congenital disorders (finger anomalies, conjoined and extra fingers, cleft hand, deformed hand, etc.), repair of tendons and nerves, hand tumors, hand burns Treatment can be done through hand surgery.
Endoscopic surgery: With the help of an endoscope, facial and forehead lifts, breast prosthesis placement, and nerve and vascular surgeries have become possible.


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22/Nov/2023

Nose Aesthetics (Rhinoplasty)

Nose surgeries are performed after health problems or aesthetic concerns. It is possible to categorize health problems under two groups

1. Structural disorders in the nose

Structural disorders in the nose prevent the person from breathing properly and the nose loses its ability to fulfill this function. These possible problems significantly affect the quality of life of the person. These conditions may be genetic or may occur due to narrowing or blockage of the air ducts as a result of causes such as trauma.

2. Deformities in the nose

Similarly, deformities in the nose can be caused by genetic reasons, but can also be seen as a result of bumps, falls or similar traumas, burns or various diseases. It is also possible for deformities to cause psychological problems. Rhinoplasty provides partial or complete solution to these problems.

Nose surgeries performed for aesthetic reasons

Those who want to have a nose surgery (Rhinoplasty) for aesthetic reasons usually request that their nose shapes, which they think are not suitable for their facial structures, be changed to the shape they want. In fact, although the patient’s request is taken into consideration before the rhinoplasty operation, the physician should be the main factor in choosing the right shape with his experience and medical knowledge. The physician will make the choice that will look both aesthetically beautiful and surgically correct by taking the patient’s opinion.

In general, those who want to physically resemble popular people in the society refer to this person by applying for plastic surgery. Since the nose is one of the most important points in facial aesthetics, these requests are very common in nose surgeries. In these requests, the physician’s attitude should be to determine whether the patient really needs this aesthetics and, if necessary, to discourage the patient from this operation. However, if there is a situation that really affects the aesthetic appearance of the person or prevents him/her from feeling good, rhinoplasty is performed.

The shape of the nose is selected with the proportions determined according to the structure of the face after the measurements. Although the nose is located in the center of the face, it is actually an organ that is expected not to attract attention. When we speak face to face, we communicate by looking at the eyes and lips of the other person, we do not look at the nose. This situation shows us that the nose should be in a way that should not attract attention. For this reason, the aim of rhinoplasty will be to achieve a natural-looking result suitable for the facial structure.

Who Can Have Nose Aesthetics?

Rhinoplasty is an operation that can be performed after the end of the person’s developmental age. The nose must take its final shape and for this reason, development must be completed. In addition, the psychological aspect of this development is also examined by specialized and experienced doctors.

What is Revision Rhinoplasty Surgery?

In cases where people who have previously undergone rhinoplasty surgery are not satisfied with the result, rhinoplasty surgery is called “Revision rhinoplasty” after consulting with their physicians and after the physician deems it appropriate. Since the nose was intervened during previous surgeries, revision surgeries are more difficult than rhinoplasties performed for the first time.

What is Deviation (Nasal Curvature) Surgery?

Nasal curvature or deviation is seen in two forms. The type that concerns only the structures inside the nose is also seen. There is also a type that affects both internal and external structures and causes the appearance of curvature in the nose from the outside. This type of curvature can block the airway. However, nasal curvature does not always cause breathing problems. Insufficient oxygen intake causes the organs not to be nourished at the desired level. This situation, which also affects sleep patterns, causes deterioration in the quality of life by preventing people from resting. After the examination and taking into account the patient’s level of complaint, it is possible to obtain a better breathing and aesthetic appearance by correcting the curvatures present inside and outside.

What Should Be Considered Before Rhinoplasty Surgery?

Some medication restrictions are required before surgery. In addition, the rules applied in all general anesthesia operations apply to these operations. These rules are conveyed to the patient by the specialist doctor and health personnel.

How is Nose Surgery (Rhinoplasty) Performed?

Rhinoplasty surgeries are performed under general anesthesia. It must be performed in the operating room under hospital conditions with appropriate equipment. Surgeries are performed with closed or open technique. The operation lasts between 1-3 hours.

After Nose Surgery (Rhinoplasty)

The patient stays in the hospital for one night as a precaution. In some cases, temporary bruising and swelling occur after nose surgery. However, this condition disappears after a certain period of time. If a tampon is placed, the tampon is removed after 2-4 days. The splints placed on the nose are removed on the 6th-8th days when bone healing is thought to be partially realized. If open rhinoplasty is performed, healing is seen by leaving a vague scar.

During the first few days, it is possible to see very slight leaks and mild congestion. In the first month, there may also be swelling in the nose that may slightly affect breathing due to edema due to surgery. This swelling is removed with medications recommended by the doctor.

The duration of postoperative return to work varies according to the technique of the surgery, the procedures performed, the patient’s healing potential, the patient’s job and the environment in which he/she lives. If patients who work at a desk do not care about the appearance of their nasal splints, they can go back to work on the fourth day. For people who work very actively, it is recommended to start working between 7-10 days.

Smoking negatively affects the healing process. Some external factors should also be taken into consideration during the treatment process. It should be protected from sunlight for 3 months. Since there is no incision after closed surgeries, there is no need to take extra protection against sunlight, but it should not be forgotten that protection from the sun is always important to prevent premature aging of the skin. Swimming, running and similar activities are restricted for certain periods depending on the procedures and technique. It is recommended to get separate information from the doctor about the use of contact lenses and glasses.

Complete recovery after rhinoplasty takes place after 3-6 months.


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20/Oct/2023

We have compiled some information about beard transplantation and hair transplantation in Turkey.

Beard transplantation is the name given to the process of transplanting hair follicles taken from the back of the hair or from another part of the body that is deemed appropriate to the beardless parts of the face. Beard transplantation is performed under local anesthesia, just like hair transplantation, and the number of grafts deemed appropriate by the physician is transplanted to the beardless area. Today, procedures such as beard and mustache transplantation, which are fashionable today, are applied by hair transplant specialist doctors working in ventum clinic hair transplantation and hair health clinic. Steps are applied in beard transplantation as in hair transplantation. Below, we will try to briefly inform you about the stages of beard transplantation.

Beard Transplant Stages

Beard transplantation is also a hair transplant procedure. In this application, a process path is followed in the same way. It is possible to briefly explain these procedures respectively as follows;

  • Preliminary examination before beard transplantation,
  • Determination of the area to be transplanted and calculation of the number of grafts,
  • Blood collection and tests before beard transplantation,
  • Providing local anesthesia with a painless anesthesia procedure,
  • Hair follicles are collected from the donor area and kept in transplant solution,
  • Transplantation of the collected grafts to the beardless area with sapphire percutaneous beard transplantation technique,

It is easy to see from these steps that beard transplantation is not much different from hair transplantation. The point to be considered here is that the hair follicles taken from the donor area are preserved with the technique that ensures the highest possible survival and transplanted to the area to be transplanted. In addition to beard transplantation, mustache transplantation is also considered in the same category. In this context, mustache transplantation and beard transplantation procedures are similar.

Advantages and Disadvantages of Hair Transplantation

As with any aesthetic procedure, beard transplantation should be considered with its advantages and disadvantages. We would like to transparently explain these advantages and disadvantages to you in this article and help you in your selection and decision phase.

Beards in the Style You Want

During beard transplantation, you can imagine your beard in any way you want. If you dream of a western type beard, you can have it drawn in that way, and if you dream of a beard with clearer lines, you can create your own style by specifying this to the physician.

It is in your hands to be more attractive with your bushy beard

Beards and moustaches are two elements that really complement a man’s aesthetics. According to researches, it has been revealed that many women find bearded men more attractive. Therefore, you have a very good advantage here.

Minimal Pain

With the developing technology and gold-tipped needles developed by the ventum clinic R&D team, you can have beard transplantation with the sapphire percutaneous method that causes the least damage to the tissue.

Fast Beard Regeneration and Recovery

After beard transplantation, golden cream is applied as in hair transplantation. With this cream, the regeneration of the tissue is faster, as a result of the researches we have done.

You can continue shaving normally after beard transplantation

Of course, you must be wondering whether there will be any change in your shaving after beard transplantation. Yes, there is no obstacle to shaving, you can continue to shave as you wish, taking into account the time your doctor gives you after the procedure. You may even enjoy shaving even more

What are the Disadvantages of Beard Transplantation?

It is useful to dwell on this issue a little bit. We believe that by focusing on it briefly, we will be more transparent and we will be more effective in your choice. Although it will be inconspicuous, we will collect grafts from the appropriate part of your body to be transplanted into the beardless area. Therefore, you will have to sacrifice the strong hair in this area. Don’t worry, we collect it so cheaply that it is not noticeable.

Transplanted beards shed between 2 weeks and 3 months

The transplanted area can be cut with scissors at the ends for the first month. After 1 month, you can shave with a razor if you wish. Transplanted beards should not be shaved with a machine for at least 6 months. After shedding, your beards will continue to grow more lushly in the normal order.

Things to Consider When Choosing a Beard Transplant Center

You want a beard transplant and you can’t decide which clinic is the best. You are right, because this is a procedure that should be done in experienced hands and will contribute to your aesthetics. It is your right to look better and to have this procedure done by experienced hands. Therefore, you should pay attention to the following criteria in the clinic you choose;

  • Choose clinics with trained and competent hair transplant specialist doctors,
  • Experience is very important. Entrust yourself to experienced doctors,
  • Ask about the technique used. Sapphire percutaneous technique should be preferred.
  • Check the clinic’s authorization documents. It must have certificates to perform hair transplantation,
  • The team you will deal with before and after beard transplantation is also important. Prefer corporate hospitals,
  • Prefer hospitals that carry out examination processes meticulously,
  • Request and compare before and after beard transplant photos,
  • Check customer reviews, be sure to Google what former clients of the clinic have written

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